Hemodynamic effects of adrenal medullectomy in the dog.

HARAKAL, CONCETTA,MARCUS M. REIDENBERG,ROGER W. SEW, AND EDWIN A. OHLER. Hemodynamic effects of adrenal medullectomy in the dog. Am. J. Physiol. 210(r): 5-6. I g66.-Adrenal medullas were successfully removed from dogs leaving intact, functioning adrenal cortical tissue on one side. Following medullectomy there was a decrease in cardiac output and an increase in total peripheral resistance, but the changes were much less in magnitude than those reported following total adrenalectomy. Blood pressure was maintained or even increased following medullectomy, in marked contrast to the hypotension seen following total adrenalectomy.